A 63 year old Female with a Smoking History and Lung Nodules
Qing Kay Li MD PhD
Presentation Date: March 1, 2016; Expires: March 31, 2019
Describe key morphological features in major malignant lung neoplasm fine needle aspiration (FNA) cytology.
Discuss main differential diagnosis of primary and metastatic lung neoplasm in FNA cytology.
Understand the importance of cytomorphological, immunohistochemical and clinical correlation in FNA cases.
The patient was a 63 year old Caucasian female who presented with a one-month history of dry cough and low-grade fever. The patient was an ex-smoker with a 2-pack per day smoking history for 20 years, having quit 10 years ago. Her past medical history was significant for a left laparoscopic radical nephrectomy several years ago due to a ‚?omass‚?Ě. On the physical examine, her lungs were clear to auscultation and percussion bilaterally and there was no lymphadenopathy or other abnormalities found. The chest X-ray revealed two lung nodules. CT scans of chest and abdomen were subsequently performed. Her chest CT revealed two infiltrating lung nodules on the right up lobe (1.2 cm) and left lower lobe (2.3 cm). Her renal CT revealed the status post left nephrectomy with postsurgical change and no evidence of malignancy in the surgical bed. A CT-guided transthoracic FNA of the left lower lobe of lung nodule was performed.