Multiple Pulmonary Nodules and Bilateral Pleural Effusions in a 76-year-old Male
Amanda K. Martin, MD, MPH and Ellen J. Giampoli, MD
Presentation Date: April 1, 2016; Expires: April 30, 2019
Review the cytomorphology of this particular entity
Recognize some of the unique risk factors for developing this entity
Understand the key clinical features of this particular entity
A 76-year-old male presented to his primary care provider with progressive cough and shortness of breath. He also reported a 20-lb unintentional weight loss over the past 6 months. A chest X-ray showed multiple pulmonary nodules and bilateral pleural effusions (right greater than left), and a subsequent PET scan revealed that several of the lung nodules were hypermetabolic. The patient agreed to undergo an endobronchial ultrasound-guided (EBUS) fine needle aspiration (FNA). Upon immediate assessment of Diff-Quik smear preparations, a preliminary diagnosis of ‚?opositive for malignancy‚?Ě was rendered. Unstained smears were collected in ethanol fixative for Papanicoulaou staining, with additional material collected in saline for preparation of a formalin-fixed cell block. Based on the images shown below, what is your diagnosis?